|
名稱(chēng)
|
Human TNF-alpha / TNFA Protein/重組人 TNF-alpha /
|
|
規(guī)格
|
20ug
|
|
編號(hào)
|
CZDB-006
|
|
價(jià)格
|
詢價(jià)
|
|
中文名
|
Human TNF-alpha / TNFA Protein/重組人 TNF-alpha /
|
|
分子別稱(chēng)
|
TNF-alpha, TNF-a, Cachectin, DIF, TNFA, TNFSF2
|
|
分子種屬
|
Human |
|
表達(dá)標(biāo)簽
|
His，S
|
|
表達(dá)宿主
|
E. coli
|
|
濃度
|
> 95 % as determined by SDS-PAGE
|
|
緩沖液
|
Lyophilized from sterile PBS, pH 7.4
|
|
存儲(chǔ)條件
|
-70°C，應(yīng)避免反復(fù)凍融。
|
|
基本描述
|
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.
|
